17 Best Peptide Serums of 2024, According to Dermatologists

Determine your skin type.
The right peptide serum for you (and any skincare product ever, really) comes down to your skin type. So if you've got oily skin, then you probably won't love a peptide serum filled with sealing oils and heavy moisturizers. In this case, opt for a lightweight peptide serum with humectants (like hyaluronic acid and glycerin) to hydrate your skin without making it greasy.
However, if you're working with dry, dehydrated skin, obviously, the more moisture a formula can provide, the better. Look for peptide serums that are loaded with hydrators, plus sealing oils to help lock in all that water and hydration you're flooding into your skin.
Look for additional benefits.
Peptides are great, but it's even better when the formula combines them with hydrators, soothers, and sometimes even exfoliants. Generally, your best bet is a peptide serum with hyaluronic acid, which will also help pull water into your skin to make it look even more plump. But I've also included a mix of options above—including exfoliating peptide serums to combine a bit of gentle, chemical buffing to get rid of dead skin that can make your skin look dull, as well as calming options that use aloe vera, cica, and/or allantoin to bring down swelling and inflammation.
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